| E123 | Easy as One, Two, Three |
| EAK | Eating at Keyboard |
| EE | Electronic Emission |
| effin | it means: f***ing |
| EFT | Electronic Funds Transfer |
| EG | Evil Grin |
| EL | Evil Laugh |
| EM | Excuse Me |
| EMA | E-Mail Address |
| EMFBI | Excuse Me For Butting In |
| EMI | Excuse My Ignorance |
| EML | Email Me Later |
| EMRTW | Evil Monkey's Rule The World |
| EMSG | E-Mail Message |
| EOD | End Of Day |
| EOM | End Of Message |
| EOT | End Of Thread (meaning: end of discussion) |
| ESADYFA | Eat Sh** And Die You F***ing Asshole |
| ESEMED | Every Second Every Minute Every Day |
| ESH | Experience, Strength, and Hope |
| ESMF | Eat Sh** Mother F***er |
| ESO | Equipment Smarter than Operator |
| ETA | Estimated Time of Arrival -or- Edited To Add |
| ETLA | ETLA Extended Three-Letter Acronym (that is, an FLA) |
| EVRE1 | Every One |
| EWI | E-mailing While Intoxicated |
| EZ | Easy |
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